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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Semicarbazide-cadmium therapy ： ウィキペディア英語版 Semicarbazide-cadmium therapy Semicarbazide-cadmium therapy was an experimental cancer therapy that was tested in several clinical trials in the Soviet Union during the 1960s. Semicarbazide is an irreversible inhibitor of semicarbazide-sensitive amine oxidase (SSAO), an enzyme possibly involved in exacerbation of inflammation. Cadmium is a heavy metal and can also induce apoptosis. The first study in humans was an open pilot trial conducted in Russia in 1957-1962.〔, abstract in ''U.S. National Library of Medicine'', and Volokhonskaya, M.L. et al. "Experience in the use of semicarbazide-cadmium therapy in patients suffering from malignant neoplasms in the incurable period", Voprosy Onkologii (U.S.S.R.); Vol: 9: No. 6, 1963 abstract in ''Energy Citations Database''.〕 It was also patented in Russia.〔Pat. №2071767, Russia. Method of treatment of oncological patients.〕 This method was successfully used for treatment of patients in later stages of lung, intestinal, and brest cancer, melanoma, and some other cancer types. The Experiments were accompanied by organizational problems (conflict between soviet authorities and scientists). == Method == The method involved the use of the following preparations: semicarbazide hydrochloride, urea, and cadmium halides. Additionally, stable isotopes of gadolinium, as gadolinium oxides, can be used, in addition to other drugs. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Semicarbazide-cadmium therapy」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.